Peyronie’s Disease and Treatment

8 Jul 2019

Peyronie’s disease is characterized by plaques made of connective tissue that form over time in the shaft of the penis, especially in its dorsal part (dosing of the penis). It is manifested by the curvature of the erect penis, usually upwards, less frequently to the sides or downwards.

In some patients, a plaque occurs that surrounds the shaft of the penis. When the penis becomes erect, plaque causes the shaft of the penis to take on a strangled appearance (hourglass appearance). This curvature can cause serious consequences, ranging from pain in the penis, short penis length to preventing sexual intercourse.

Painful erections and difficulty in sexual intercourse (erectile dysfunction), which can be seen in approximately 50% of patients, are one of the important reasons that force men with this problem to see a doctor. Curvature of the penis, erectile dysfunction and pain during erection impair the quality of life of Peyronie’s patients.

Medication and Injection therapy

Although many different drug treatments are used in Peyronie’s disease, the role of conservative treatment is still not fully defined. No medication for Peyronie’s disease has been approved by the European Medical Association.

The treatment method applied by injecting medication into the plaque that forms on the penis shaft and causes curvature does not completely eliminate the plaque, but it can be effective in improving the pain and curvature to some extent.

In severe cases where oral medication and intralesional injection treatment are not successful in Peyronie’s disease, the aim of surgical treatment is to correct the curvature and provide a satisfactory sexual intercourse. Surgery is performed in patients who have an incurable disease for at least 3 months (6-12 months according to some recommendations).

ESWT/EDSWT treatment in Peyronie’s Disease

ESWT/EDSWT treatment does not have any side effects, does not cause pain, does not harm neighboring organs, does not require anesthesia or hospitalization, does not interact with other diseases (cardiovascular diseases, hypertension, etc.) and constantly used medications, and the patient can easily continue his daily life after the procedure. It is a new generation treatment method that can
In ESWT/EDSWT treatment, low-energy acoustic shock waves that are not felt by the patient are applied. Sessions last 15 to 20 minutes and 3000 beats are given per session.

Low-energy shock waves applied with ESWT/EDSWT cause the plaque to shrink in Peyronie plaques in the acute phase with their effects on the tissue healing mechanism, while helping the regeneration of calcified Peyronie plaques in patients in the chronic phase. These remarkable effects on pain during erection and penis curvature contribute to the sexual lives of Peyronie’s patients with a quality erection, in addition to treating pain and penile curvature.